PCNT antibody (AA 3101-3200)

Catalog No. ABIN873305

The Rabbit Polyclonal anti-PCNT antibody is suitable to detect PCNT in samples from Mouse. It has been validated for ELISA, ICC, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for PCNT antibody (AA 3101-3200) (ABIN873305)

Target: PCNT (Pericentrin (PCNT))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCNT antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PCNT Antibody

Binding Specificity: AA 3101-3200

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Pericentrin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PCNT

Target: PCNT (Pericentrin (PCNT))

Alternative Name: PCNT

Background:

Synonyms: Centrosome Marker, Ken, Kendrin, KIAA0402, MOPD2, PCN, PCNT 2, PCNT, PCNT B, PCNT1, PCNT2, PCNTB, PCTN2, Pericentrin 1, Pericentrin 1, Pericentrin 2, Pericentrin 380, Pericentrin B, SCKL4.

Background: The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. [provided by RefSeq, Jul 2008].

Gene ID: 5116

Pathways: Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interactome