HBXIP antibody (AA 41-91)

Catalog No. ABIN873319

This Rabbit Polyclonal antibody specifically detects HBXIP in ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for HBXIP antibody (AA 41-91) (ABIN873319)

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBXIP antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HBXIP Antibody

Binding Specificity: AA 41-91

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HBXIP

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HBXIP

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Alternative Name: HBXIP

Target Type: Viral Protein

Background:

Synonyms: HBV X interacting protein, HBX interacting protein, Hepatitis B virus X interacting protein, MGC71071, XIP, HBXIP_HUMAN.

Background: HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.

Gene ID: 10542

Pathways: PI3K-Akt Signaling, Regulation of Cell Size