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Endoglin antibody (AA 601-658) (AbBy Fluor® 350)

The Rabbit Polyclonal anti-Endoglin antibody has been validated for FACS, IF (cc) and IF (p). It is suitable to detect Endoglin in samples from Human and Rat.
Catalog No. ABIN888674

Quick Overview for Endoglin antibody (AA 601-658) (AbBy Fluor® 350) (ABIN888674)

Target

See all Endoglin (ENG) Antibodies
Endoglin (ENG)

Reactivity

  • 209
  • 71
  • 66
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  • 16
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Human, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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  • 1
  • 1
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This Endoglin antibody is conjugated to AbBy Fluor® 350

Application

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Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    AA 601-658

    Predicted Reactivity

    Mouse,Dog,Cow,Pig,Horse,Chicken

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CD105

    Isotype

    IgG
  • Application Notes

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C/-80 °C

    Storage Comment

    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

    Expiry Date

    12 months
  • Target

    Endoglin (ENG)

    Alternative Name

    CD105

    Background

    Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

    Subcellular location: Cell membrane

    Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

    Gene ID

    2022

    UniProt

    P17813
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