ICMT antibody (C-Term) (Cy3)

Catalog No. ABIN891458

The Rabbit Polyclonal anti-ICMT antibody is suitable to detect ICMT in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for ICMT antibody (C-Term) (Cy3) (ABIN891458)

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICMT antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ICMT Antibody (Cy3)

Binding Specificity: AA 211-278, C-Term

Purpose: ICMT Polyclonal Antibody, Cy3 Conjugated

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Human ICMT (C-terminus)

Isotype: IgG

Application Details

Application Notes: WB(1:500-1000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ICMT

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Alternative Name: ICMT

Background:

Synonyms: HSTE14, Icmt, ICMT_HUMAN, Isoprenylcysteine carboxylmethyltransferase, pcCMT, PCMT, PPMT, Prenylated protein carboxyl methyltransferase, Prenylcysteine carboxyl methyltransferase, Protein-S-isoprenylcysteine O-methyltransferase

Background: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.Tissue specificity:Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons.

Gene ID: 23463

UniProt: O60725