GAS6 antibody (AA 551-650) (AbBy Fluor® 350)

Catalog No. ABIN898377

This anti-GAS6 antibody is a Rabbit Polyclonal antibody detecting GAS6 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Pig.

Quick Overview for GAS6 antibody (AA 551-650) (AbBy Fluor® 350) (ABIN898377)

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Reactivity: Human, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS6 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GAS6 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 551-650

Cross-Reactivity: Human, Mouse, Pig

Predicted Reactivity: Rat,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GAS 6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GAS6

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Alternative Name: GAS 6

Background:

Synonyms: AXSF, AXLLG, Growth arrest-specific protein 6, GAS-6, AXL receptor tyrosine kinase ligand, GAS6

Background: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Gene ID: 2621

UniProt: Q14393

Pathways: RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response