GMCL1L antibody (AA 351-450) (FITC)

Catalog No. ABIN899284

This Rabbit Polyclonal antibody specifically detects GMCL1L in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for GMCL1L antibody (AA 351-450) (FITC) (ABIN899284)

Target: GMCL1L (GMCL1P1) (Germ Cell-Less, Spermatogenesis Associated 1 Pseudogene 1 (GMCL1P1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMCL1L antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GMCL1L Antibody (FITC)

Binding Specificity: AA 351-450

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMCL1L

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GMCL1L

Target: GMCL1L (GMCL1P1) (Germ Cell-Less, Spermatogenesis Associated 1 Pseudogene 1 (GMCL1P1))

Alternative Name: GMCL1L

Background:

Synonyms: GCL, Germ cell less homolog 1 Drosophila like, Germ cell less protein like 1 like, GMCL 2, GMCL2, GMCLL_HUMAN.

Background: GMCL1L has a possible function in spermatogenesis. It enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport. GMCL1L is also a probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Gene ID: 64396