INSC antibody (AA 201-300) (HRP)

Catalog No. ABIN902785

This Rabbit Polyclonal antibody specifically detects INSC in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for INSC antibody (AA 201-300) (HRP) (ABIN902785)

Target: INSC (Inscuteable Homolog (INSC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSC antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-INSC Antibody (HRP)

Binding Specificity: AA 201-300

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human INSC

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for INSC

Target: INSC (Inscuteable Homolog (INSC))

Alternative Name: INSC

Background:

Synonyms: Insc, INSC_HUMAN, Inscuteable homolog Drosophila, Protein inscuteable homolog.

Background: May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium.Tissue specificity:Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas.

Gene ID: 387755