CD11b antibody (AA 520-570) (AbBy Fluor® 555)

Catalog No. ABIN902950

This Rabbit Polyclonal antibody specifically detects CD11b in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CD11b antibody (AA 520-570) (AbBy Fluor® 555) (ABIN902950)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD11b antibody is conjugated to AbBy Fluor® 555

Application: Flow Cytometry (FACS)

Product Details anti-CD11b Antibody (AbBy Fluor® 555)

Binding Specificity: AA 520-570

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD11c

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: Cd11b/C

Background:

Synonyms: CD11C, SLEB6, Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p15,95 alpha chain, Leukocyte adhesion receptor p15,95, ITGAX

Background: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Gene ID: 3687

UniProt: P20702

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation