JAG1 antibody (AbBy Fluor® 555)

Catalog No. ABIN903210

This anti-JAG1 antibody is a Rabbit Polyclonal antibody detecting JAG1 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for JAG1 antibody (AbBy Fluor® 555) (ABIN903210)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG1 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-JAG1 Antibody (AbBy Fluor® 555)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Jagged1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: Jagged1

Background:

Synonyms: JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1,MGC104644, Ser 1, CD 339, CD339, CD339 antigen, Headturner, Htu, Jag 1, Jagged-1, Jagged 1, Jagged 1 Alagille syndrome, JAGL1, Ser-1, Ser1, Serrate-1, Slalom.

Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq].

Gene ID: 182

Pathways: Notch Signaling, Stem Cell Maintenance