MRPL39 antibody (AA 151-250) (AbBy Fluor® 647)

Catalog No. ABIN907010

The Rabbit Polyclonal anti-MRPL39 antibody has been validated for IF (cc) and IF (p). It is suitable to detect MRPL39 in samples from Human.

Quick Overview for MRPL39 antibody (AA 151-250) (AbBy Fluor® 647) (ABIN907010)

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL39 antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MRPL39 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 151-250

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MrpL-39

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MRPL39

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Alternative Name: MrpL39

Background:

Synonyms: L39mt, Mitochondrial ribosomal protein L39, MRP L5, MRPL5, MSTP003, PRED22, PRED66, RPML5, RM39_HUMAN.

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

Gene ID: 54148