NLRP10 antibody (AA 401-500) (Cy3)

Catalog No. ABIN908459

The Rabbit Polyclonal anti-NLRP10 antibody has been validated for IF (cc) and IF (p). It is suitable to detect NLRP10 in samples from Human.

Quick Overview for NLRP10 antibody (AA 401-500) (Cy3) (ABIN908459)

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP10 antibody is conjugated to Cy3

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NLRP10 Antibody (Cy3)

Binding Specificity: AA 401-500

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLRP10

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Alternative Name: NLRP10

Background:

Synonyms: CLR11.1, NACHT, leucine rich repeat and PYD containing 10, NACHT, LRR and PYD domains containing protein 10, NACHT, LRR and PYD domains-containing protein 10, NAL10_HUMAN, NALP10, NLR family, pyrin domain containing 10, Nlrp10, NOD8,Nucleotide-binding oligomerization domain protein 8, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10, PAN5, PYNOD.

Background: Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.Tissue specificity: Widely expressed with highest levels in heart, brain and skeletal muscle.

Gene ID: 338322

Pathways: Inflammasome