NLRP7 antibody (AA 901-980) (Cy3)

Catalog No. ABIN908480

The Rabbit Polyclonal anti-NLRP7 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect NLRP7 in samples from Human.

Quick Overview for NLRP7 antibody (AA 901-980) (Cy3) (ABIN908480)

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP7 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NLRP7 Antibody (Cy3)

Binding Specificity: AA 901-980

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLRP7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NLRP7

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Alternative Name: NLRP7

Background:

Synonyms: CLR19.4, FLJ94610, HYDM, NACHT, leucine rich repeat and PYD containing 7, NACHT, LRR and PYD containing protein 7, NACHT, LRR and PYD domains containing protein 7, NACHT, LRR and PYD domains-containing protein 7, NALP7, NALP7_HUMAN, NLR family, pyrin domain containing 7, NLRP7, NOD12, Nucleotide-binding oligomerization domain protein 12, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7, PAN7, PYPAF3, PYRIN-containing APAF1-like protein 3.

Background: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Gene ID: 199713

Pathways: Inflammasome