TLR11 antibody (Internal Region)

Catalog No. ABIN920631

The Rabbit Polyclonal anti-TLR11 antibody (ABIN920631) specifically detects TLR11 in WB and ICC. The antibody is reactive with Mouse samples.

Quick Overview for TLR11 antibody (Internal Region) (ABIN920631)

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR11 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-TLR11 Antibody

Binding Specificity: Internal Region

Characteristics: Positive Control: RAW26.7 cell lysate. Located in membrane.

Purification: Antigen Immunoaffinity purified

Immunogen: Rabbit polyclonal TLR11 antibody was raised against a peptide corresponding to 16 amino acids near the middle of mouse TLR11.

Isotype: IgG

Application Details

Application Notes: Western blot: use at 0.5-2 µg/mL

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.02% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TLR11

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Background: Toll-like receptors (TRLs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TRL11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacterial, and mice lacking TLR11 showed a much greater susceptibility to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. Synonyms:

Molecular Weight: 106 kDa

Pathways: Activation of Innate immune Response