RAD17 antibody (C-Term)

Catalog No. ABIN925763

The Rabbit Polyclonal anti-RAD17 antibody has been validated for WB. It is suitable to detect RAD17 in samples from Human, Mouse, Rat, Dog and Cow.

Quick Overview for RAD17 antibody (C-Term) (ABIN925763)

Target: RAD17

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAD17 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine)

Immunogen: RAD17 antibody was raised in rabbit using the C terminal of RAD17 as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RAD17 Blocking Peptide, (ABIN5615728), is also available for use as a blocking control in assays to test for specificity of this RAD17 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RAD17

Target: RAD17

Alternative Name: RAD17

Background: RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. Synonyms: Polyclonal RAD17 antibody, Anti-RAD17 antibody, RAD17 homolog, S. pombe antibody, CCYC antibody, HRAD17 antibody, R24L antibody, RAD17Sp antibody, Rad24 antibody.