KEAP1 antibody (C-Term)

Catalog No. ABIN925797

The Rabbit Polyclonal anti-KEAP1 antibody (ABIN925797) specifically detects KEAP1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Pig, Cow, Dog, Zebrafish (Danio rerio) and Xenopus laevis samples.

Quick Overview for KEAP1 antibody (C-Term) (ABIN925797)

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KEAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KEAP1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Pig (Porcine), Zebrafish (Brachydanio rerio), Frog

Immunogen: KEAP1 antibody was raised in rabbit using the C terminal of KEAP1 as the immunogen

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

KEAP1 Blocking Peptide, (ABIN5614314), is also available for use as a blocking control in assays to test for specificity of this KEAP1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for KEAP1

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Alternative Name: KEAP1

Background: KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Synonyms: Polyclonal KEAP1 antibody, Anti-KEAP1 antibody, kelch-like ECH-associated protein 1 antibody, INrf2 antibody, KIAA0132 antibody, KLHL19 antibody, MGC10630 antibody, MGC1114 antibody, MGC20887 antibody, MGC4407 antibody, MGC9454 antibody.

Pathways: Maintenance of Protein Location