Gastrin-Releasing Peptide antibody

Catalog No. ABIN926137

Product Details anti-Gastrin-Releasing Peptide Antibody

Target: Gastrin-Releasing Peptide (GRP)

Reactivity: Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gastrin-Releasing Peptide antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Cross-Reactivity: Chicken

Immunogen: GRP10 antibody was raised in rabbit using Bombesin conjugated to BSA as the immunogen.

Application Details

Application Notes: IF: 1:400 - 1:800
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Supplied in lyophilized form. Dissolve the antiserum in 50 - 100 µL distilled water and dilute further in 0.1 M PBS with 1 % BSA and 0.1 % Na-azide

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Gastrin-Releasing Peptide

Target: Gastrin-Releasing Peptide (GRP)

Alternative Name: GRP10 (GRP Products)

Synonyms: BLP antibody, GRP antibody, BN antibody, GRP-10 antibody, preproGRP antibody, proGRP antibody, gastrin releasing peptide antibody, Grp antibody, GRP antibody

Background: Bombesin is a 14-amino acid peptide originally isolated from the skin of a frog. It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide. It stimulates gastrin release from G cells and activates three different G-protein-coupled receptors known as BBR1, -2, and -3. It also activates these receptors in the brain. Together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour. Synonyms: Polyclonal GRP10 antibody, Anti GRP10 antibody, Bombesin antibody, BN antibody, Neuromedin C antibody.

Pathways: Peptide Hormone Metabolism, Hormone Activity