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Hexosaminidase A antibody (C-Term)

The Rabbit Polyclonal anti-Hexosaminidase A antibody has been validated for WB. It is suitable to detect Hexosaminidase A in samples from Human.
Catalog No. ABIN926663

Quick Overview for Hexosaminidase A antibody (C-Term) (ABIN926663)

Target

See all Hexosaminidase A (HEXA) Antibodies
Hexosaminidase A (HEXA)

Reactivity

  • 61
  • 27
  • 15
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 52
  • 15
Rabbit

Clonality

  • 54
  • 13
Polyclonal

Conjugate

  • 46
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Hexosaminidase A antibody is un-conjugated

Application

  • 55
  • 34
  • 19
  • 8
  • 8
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 9
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Purification

    Purified

    Immunogen

    HEXA antibody was raised in rabbit using the C terminal of HEXA as the immunogen
  • Application Notes

    Optimal conditions should be determined by the investigator.

    Comment

    HEXA Blocking Peptide, (ABIN5613994), is also available for use as a blocking control in assays to test for specificity of this HEXA antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Concentration

    Lot specific

    Buffer

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target

    Hexosaminidase A (HEXA)

    Alternative Name

    HEXA

    Background

    This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). Synonyms: Polyclonal HEXA antibody, Anti-HEXA antibody, hexosaminidase A, alpha polypeptide antibody, MGC99608 antibody, TSD antibody.

    Pathways

    Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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