NQO1 antibody (Middle Region)

Catalog No. ABIN926681

The Rabbit Polyclonal anti-NQO1 antibody has been validated for WB. It is suitable to detect NQO1 in samples from Human.

Quick Overview for NQO1 antibody (Middle Region) (ABIN926681)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NQO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NQO1 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: NQO1 antibody was raised in rabbit using the middle region of NQO1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

NQO1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NQO1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Alternative Name: NQO1

Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Synonyms: Polyclonal NQO1 antibody, Anti-NQO1 antibody, NADPH dehydrogenase, quinone 1 antibody, DHQU antibody, DIA4 antibody, DTD antibody, NMOR1 antibody, NMORI antibody, QR1 antibody.