CD70 antibody (N-Term)

Catalog No. ABIN926714

Product Details anti-CD70 Antibody

Target: CD70 (CD70 Molecule (CD70))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CD70 antibody was raised in rabbit using the N terminal of CD70 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

CD70 Blocking Peptide, catalog no. 33R-10423, is also available for use as a blocking control in assays to test for specificity of this CD70 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70 (CD70 Products)

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. Synonyms: Polyclonal CD70 antibody, Anti-CD70 antibody, CD70 molecule antibody, CD27L antibody, CD27LG antibody, TNFSF7 antibody.

Pathways: Cancer Immune Checkpoints