GBA antibody (C-Term)

Catalog No. ABIN926718

Product Details anti-GBA Antibody

Target: GBA (Glucosidase, Beta, Acid (GBA))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: GBA antibody was raised in rabbit using the C terminal of GBA as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

GBA Blocking Peptide, catalog no. 33R-10317, is also available for use as a blocking control in assays to test for specificity of this GBA antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Alternative Name: GBA (GBA Products)

Synonyms: GBA1 antibody, GCB antibody, GLUC antibody, BETA-GLUCOSIDASE antibody, T12J13.8 antibody, T12J13_8 antibody, beta glucosidase 25 antibody, PSPTO3318 antibody, PSPTO4290 antibody, GC antibody, GCase antibody, betaGC antibody, glucosylceramidase beta antibody, beta glucosidase 25 antibody, beta-glucosidase antibody, Beta-glucosidase antibody, glucosidase, beta, acid antibody, glucosylceramidase antibody, bglX-2 antibody, GBA antibody, BGLU25 antibody, PSPTO_3318 antibody, bglX antibody, bglA4 antibody, Gba antibody, LOC100399524 antibody, bglA.2 antibody, bglX-2 antibody

Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. Synonyms: Polyclonal GBA antibody, Anti-GBA antibody, glucosidase, beta, acid antibody, GBA1 antibody, GCB antibody, GLUC antibody.

Pathways: Cellular Glucan Metabolic Process