CDC25C antibody (N-Term)

Catalog No. ABIN926902

This Rabbit Polyclonal antibody specifically detects CDC25C in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CDC25C antibody (N-Term) (ABIN926902)

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC25C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDC25C Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Purified

Immunogen: CDC25 C antibody was raised in rabbit using the N terminal of CDC25 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CDC25C Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CDC25C antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CDC25C

Target: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Alternative Name: CDC25C

Background: CDC25C gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. Synonyms: Polyclonal CDC25C antibody, Anti-CDC25C antibody, cell division cycle 25 homolog C, S. pombe antibody, CDC25 antibody.

Pathways: Cell Division Cycle, M Phase