RAB8A antibody (Middle Region)

Catalog No. ABIN926981

The Rabbit Polyclonal anti-RAB8A antibody has been validated for WB. It is suitable to detect RAB8A in samples from Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken and Xenopus laevis.

Quick Overview for RAB8A antibody (Middle Region) (ABIN926981)

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB8A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAB8A Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Dog (Canine), Mouse (Murine), Rat (Rattus), Frog, Chicken, Cow (Bovine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: RAB8 A antibody was raised in rabbit using the middle region of RAB8 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RAB8A Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this RAB8A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RAB8A

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Alternative Name: RAB8A

Background: RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. Synonyms: Polyclonal RAB8A antibody, Anti-RAB8A antibody, RAB8A, member RAS oncogene family antibody, MEL antibody, RAB8 antibody.

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome