TLE2 antibody (N-Term)

Catalog No. ABIN927371

The Rabbit Polyclonal anti-TLE2 antibody has been validated for WB. It is suitable to detect TLE2 in samples from Human, Mouse and Rat.

Quick Overview for TLE2 antibody (N-Term) (ABIN927371)

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TLE2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Purified

Immunogen: TLE2 antibody was raised in rabbit using the N terminal of TLE2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TLE2 Blocking Peptide, (ABIN5616624), is also available for use as a blocking control in assays to test for specificity of this TLE2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TLE2

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Alternative Name: TLE2

Background: TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Synonyms: Polyclonal TLE2 antibody, Anti-TLE2 antibody, transducin-like enhancer of split 2, E, sp1 homolog, Drosophila antibody, ESG antibody, ESG2 antibody, FLJ41188 antibody, GRG2 antibody.

Pathways: WNT Signaling