RENT2/UPF2 antibody (N-Term)

Catalog No. ABIN927943

This Rabbit Polyclonal antibody specifically detects RENT2/UPF2 in WB. It exhibits reactivity toward Human.

Quick Overview for RENT2/UPF2 antibody (N-Term) (ABIN927943)

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RENT2/UPF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RENT2/UPF2 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: UPF2 antibody was raised in rabbit using the N terminal of UPF2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RENT2/UPF2

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Alternative Name: UPF2

Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein. Synonyms: Polyclonal UPF2 antibody, Anti-UPF2 antibody, UPF2 regulator of nonsense transcripts homolog, yeast antibody, DKFZp434D222 antibody, HUPF2 antibody, KIAA1408 antibody, MGC138834 antibody, MGC138835 antibody, RENT2 antibody, smg-3 antibody.