POLR3C antibody (Middle Region)

Catalog No. ABIN928607

Product Details anti-POLR3C Antibody

Target: POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR3C antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: POLR3 C antibody was raised in rabbit using the middle region of POLR3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

POLR3C Blocking Peptide, catalog no. 33R-9487, is also available for use as a blocking control in assays to test for specificity of this POLR3C antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for POLR3C

Target: POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))

Alternative Name: POLR3C (POLR3C Products)

Synonyms: rpc3 antibody, rpc62 antibody, 4933407E01Rik antibody, RPC3 antibody, RPC62 antibody, zgc:56348 antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog antibody, RNA polymerase III subunit C antibody, polymerase (RNA) III (DNA directed) polypeptide C (62kD) antibody, polymerase (RNA) III (DNA directed) polypeptide C antibody, polr3c.S antibody, POLR3C antibody, polr3c antibody, Polr3c antibody

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3C is a specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. POLR3C may direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. POLR3C may be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Synonyms: Polyclonal POLR3C antibody, Anti-POLR3C antibody, polymerase, RNA III, DNA directed polypeptide C, 62kD antibody, RPC3 antibody, RPC62 antibody.