PFKFB2 antibody (C-Term)

Catalog No. ABIN928877

The Rabbit Polyclonal anti-PFKFB2 antibody is suitable to detect PFKFB2 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for PFKFB2 antibody (C-Term) (ABIN928877)

Target: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKFB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PFKFB2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Pfkfb2 antibody was raised in rabbit using the C terminal of Pfkfb2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Pfkfb2 Blocking Peptide, (ABIN937982), is also available for use as a blocking control in assays to test for specificity of this Pfkfb2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PFKFB2

Target: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Alternative Name: Pfkfb2

Background: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a  regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase  activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that  catalyzes the degradation of fructose-2,6-bisphosphate. Synonyms: Polyclonal Pfkfb2 antibody, Anti-Pfkfb2 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 antibody, 4930568D07Rik antibody.

Pathways: PI3K-Akt Signaling, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process