RAD51 Homolog B antibody (Middle Region)

Catalog No. ABIN928985

The Rabbit Polyclonal anti-RAD51 Homolog B antibody has been validated for WB. It is suitable to detect RAD51 Homolog B in samples from Human.

Quick Overview for RAD51 Homolog B antibody (Middle Region) (ABIN928985)

Target: RAD51 Homolog B (Rad51B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD51 Homolog B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAD51 Homolog B Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: RAD51 L1 antibody was raised in rabbit using the middle region of RAD51 1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RAD51L1 Blocking Peptide, (ABIN939488), is also available for use as a blocking control in assays to test for specificity of this RAD51L1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Alternative Name: RAD51L1

Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Synonyms: Polyclonal RAD51L1 antibody, Anti-RAD51L1 antibody, RAD51-like 1, S. cerevisiae antibody, MGC34245 antibody, R51H2 antibody, RAD51B antibody, REC2 antibody, hREC2 antibody.

Pathways: DNA Damage Repair