APP antibody (C-Term)

Catalog No. ABIN929066

The Rabbit Polyclonal anti-APP antibody is suitable to detect APP in samples from Human and Mouse. It has been validated for WB.

Quick Overview for APP antibody (C-Term) (ABIN929066)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APP Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: App antibody was raised in rabbit using the C terminal of App as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

App Blocking Peptide, (ABIN5612127), is also available for use as a blocking control in assays to test for specificity of this App antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: App

Background: App functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions. Synonyms: Polyclonal App antibody, Anti-App antibody, amyloid beta, A4 precursor protein antibody, Abeta antibody, Abpp antibody, Adap antibody, Ag antibody, betaApp antibody, Cvap antibody, E030013M08Rik antibody.

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour