CASP5 antibody (Middle Region)
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- Target See all CASP5 Antibodies
- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CASP5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- CASP5 antibody was raised in rabbit using the middle region of CASP5 as the immunogen
- Top Product
- Discover our top product CASP5 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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CASP5 Blocking Peptide, catalog no. 33R-9599, is also available for use as a blocking control in assays to test for specificity of this CASP5 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
- Alternative Name
- CASP5 (CASP5 Products)
- Synonyms
- ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, CASP5 antibody, caspase 5 antibody, caspase-5 antibody, CASP5 antibody, LOC100437308 antibody
- Background
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. Synonyms: Polyclonal CASP5 antibody, Anti-CASP5 antibody, caspase 5, apoptosis-related cysteine peptidase antibody, ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, MGC141966 antibody.
- Pathways
- Inflammasome
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