COPS6 antibody (Middle Region)

Catalog No. ABIN929209

This Rabbit Polyclonal antibody specifically detects COPS6 in WB. It exhibits reactivity toward Human.

Quick Overview for COPS6 antibody (Middle Region) (ABIN929209)

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COPS6 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: COPS6 antibody was raised in rabbit using the middle region of COPS6 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for COPS6

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Alternative Name: COPS6

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. Synonyms: Polyclonal COPS6 antibody, Anti-COPS6 antibody, COP9 constitutive photomorphogenic homolog subunit 6, Arabidopsis antibody, CSN6 antibody, MOV34-34KD antibody.

Pathways: Cell Division Cycle