Factor VII antibody (Middle Region)

Catalog No. ABIN929427

The Rabbit Polyclonal anti-Factor VII antibody (ABIN929427) specifically detects Factor VII in WB. The antibody is reactive with Human samples.

Quick Overview for Factor VII antibody (Middle Region) (ABIN929427)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VII antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Factor VII Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: F7 antibody was raised in rabbit using the middle region of F7 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

F7 Blocking Peptide, (ABIN5613443), is also available for use as a blocking control in assays to test for specificity of this F7 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Alternative Name: F7

Background: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. Synonyms: Polyclonal F7 antibody, Anti-F7 antibody, coagulation factor VII, serum prothrombin conversion accelerator antibody.

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling