Cyclin B2 antibody

Catalog No. ABIN931031

The Mouse Monoclonal anti-Cyclin B2 antibody is suitable to detect Cyclin B2 in samples from Human. It has been validated for DB.

Quick Overview for Cyclin B2 antibody (ABIN931031)

Target: Cyclin B2 (CCNB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin B2 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 2115C1

Product Details anti-Cyclin B2 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: CCNB2 antibody was raised in mouse using recombinant Human Cyclin B2 (Ccnb2)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: CCNB2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for Cyclin B2

Target: Cyclin B2 (CCNB2)

Alternative Name: CCNB2

Background: Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. Synonyms: Monoclonal CCNB2 antibody, Anti-CCNB2 antibody, cyclin B2 antibody, HsT17299 antibody.

Pathways: Cell Division Cycle, M Phase