TAX1BP1 antibody

Catalog No. ABIN931085

The Mouse Monoclonal anti-TAX1BP1 antibody is suitable to detect TAX1BP1 in samples from Human. It has been validated for WB and DB.

Quick Overview for TAX1BP1 antibody (ABIN931085)

Target: TAX1BP1 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1 (TAX1BP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TAX1BP1 antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Clone: 3098C2a

Product Details anti-TAX1BP1 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: TAX1 BP1 antibody was raised in mouse using recombinant Human Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1 (Tax1 p1)

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: TAX1 BP1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for TAX1BP1

Target: TAX1BP1 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 1 (TAX1BP1))

Alternative Name: TAX1BP1

Background: TAX1BP1 inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. Synonyms: Monoclonal TAX1BP1 antibody, Anti-TAX1BP1 antibody, Human T-cell leukemia virus type I binding protein 1 antibody, T6BP antibody, TXBP151 antibody, CALCOCO3 antibody.

Pathways: TLR Signaling