BPTF antibody

Catalog No. ABIN931087

This Mouse Monoclonal antibody specifically detects BPTF in DB. It exhibits reactivity toward Human.

Quick Overview for BPTF antibody (ABIN931087)

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BPTF antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 2343C3a

Product Details anti-BPTF Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: FALZ antibody was raised in mouse using recombinant Human Bromodomain Phd Finger Transcription Factor (Bptf)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: FALZ antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for BPTF

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Alternative Name: FALZ

Background: This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. Synonyms: Monoclonal FALZ antibody, Anti-FALZ antibody, Bromodomain PHD finger transcription factor antibody, BPTF antibody, FAC1 antibody, NURF301 antibody.