Paired Box 3 antibody

Catalog No. ABIN931107

This anti-Paired Box 3 antibody is a Mouse Monoclonal antibody detecting Paired Box 3 in DB. Suitable for Human.

Quick Overview for Paired Box 3 antibody (ABIN931107)

Target: Paired Box 3 (PAX3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 6288D4a

Product Details anti-Paired Box 3 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: PAX3 antibody was raised in mouse using recombinant Human Paired Box Gene 3 (Waardenburg Syndrome 1) (Pax3)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PAX3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3

Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. Synonyms: Monoclonal PAX3 antibody, Anti-PAX3 antibody, Paired box 3 antibody, WS1 antibody, CDHS antibody, HUP2 antibody, MGC120381 antibody, MGC120382 antibody, MGC120383 antibody, MGC120384 antibody, MGC134778 antibody.

Pathways: Sensory Perception of Sound, Tube Formation