NEIL3 antibody

Catalog No. ABIN931131

The Mouse Monoclonal anti-NEIL3 antibody (Clone 2627C1b) (ABIN931131) specifically detects NEIL3 in DB. The antibody is reactive with Human samples.

Quick Overview for NEIL3 antibody (ABIN931131)

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEIL3 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 2627C1b

Product Details anti-NEIL3 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: NEIL3 antibody was raised in mouse using recombinant Human Nei Endonuclease Viii-Like 3 (E. Coli)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: NEIL3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for NEIL3

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Alternative Name: NEIL3

Background: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. Synonyms: Monoclonal NEIL3 antibody, Anti-NEIL3 antibody, Nei endonuclease VIII-like 3 antibody, FPG2 antibody, hFPG2 antibody, hNEI3 antibody, FLJ10858 antibody.

Pathways: DNA Damage Repair