PPARA antibody

Catalog No. ABIN931197

The Mouse Monoclonal anti-PPARA antibody (Clone 467D1a) (ABIN931197) specifically detects PPARA in DB. The antibody is reactive with Human samples.

Quick Overview for PPARA antibody (ABIN931197)

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPARA antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 467D1a

Product Details anti-PPARA Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: PPARA antibody was raised in mouse using recombinant Human Peroxisome Proliferator-Activated Receptor Alpha

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PPARA antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for PPARA

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Alternative Name: PPARA

Background: Peroxisome proliferator-activated receptor alpha (PPARalpha) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression. PPARalpha is located primarily in the liver, adipose tissue, kidney, heart, skeletal muscle and large intestine where it is thought to regulate fatty acid synthesis and oxidation, gluconeogenesis, ketogenesis and lipoprotein assembly. The human gene encoding PPARalpha has been localized to chromosome 22. Synonyms: Monoclonal PPARA antibody, Anti-PPARA antibody, Peroxisome proliferator activated receptor alpha antibody, NR1C1 antibody, hPPAR antibody, MGC2452 antibody, MGC2237 antibody.

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C