FGFR4 antibody

Catalog No. ABIN931323

The Mouse Monoclonal anti-FGFR4 antibody (Clone 4H2B10B2) (ABIN931323) specifically detects FGFR4 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for FGFR4 antibody (ABIN931323)

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGFR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 4H2B10B2

Product Details anti-FGFR4 Antibody

Immunogen: FGFR4 antibody was raised in Mouse using a purified recombinant fragment of FGFR4 expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for FGFR4

Target: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Alternative Name: FGFR4

Background: FGFR4 is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. Each receptor contains an extracellular ligand binding domain, a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the retina. Synonyms: Monoclonal FGFR4 antibody, Anti-FGFR4 antibody, FGFR-4 antibody, FGFR 4 antibody, Fibroblast growth factor receptor 4 antibody.

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding