×
For best experience we recommend to activate Javascript in your browser.
HCK antibody
HCK
Reactivity: Human
WB, ELISA, IHC
Host: Mouse
Monoclonal
3D12E10
unconjugated
Product Details anti-HCK Antibody
(hide)
Target
See all HCK Antibodies
HCK
(Hemopoietic Cell Kinase (HCK))
Reactivity
All reactivities for HCK antibodies
Human
Host
All hosts for HCK antibodies
Mouse
Clonality
All clonalities for HCK antibodies
Monoclonal
Conjugate
All conjugates for HCK antibodies
This HCK antibody is un-conjugated
Application
All applications for HCK antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Immunogen
HCK antibody was raised in Mouse using a purified recombinant fragment of HCK expressed in E. coli as the immunogen.
Clone
3D12E10
Isotype
IgG1
Top Product
Discover our top product HCK Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for HCK
(hide)
Target
HCK
(Hemopoietic Cell Kinase (HCK))
Alternative Name
HCK (HCK Products )
Synonyms
laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody
Background
HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization. Synonyms: Monoclonal HCK antibody, Anti-HCK antibody.
Pathways
Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Actin Filament Polymerization , CXCR4-mediated Signaling Events , Thromboxane A2 Receptor Signaling
Recently viewed
(hide)