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Chitotriosidase 1 antibody (AA 22-137)
CHIT1
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
1D9G2-1D9G4-2B4G3
unconjugated
Product Details anti-Chitotriosidase 1 Antibody
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Target
See all Chitotriosidase 1 (CHIT1) Antibodies
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
Binding Specificity
All epitopes for Chitotriosidase 1 antibodies
AA 22-137
Reactivity
All reactivities for Chitotriosidase 1 antibodies
Human
Host
All hosts for Chitotriosidase 1 antibodies
Mouse
Clonality
All clonalities for Chitotriosidase 1 antibodies
Monoclonal
Conjugate
All conjugates for Chitotriosidase 1 antibodies
This Chitotriosidase 1 antibody is un-conjugated
Application
All applications for Chitotriosidase 1 antibodies
Western Blotting (WB), ELISA
Immunogen
CHIT1 antibody was raised in Mouse using a purified recombinant fragment of CHIT1(aa22-137) expressed in E. coli as the immunogen.
Clone
1D9G2-1D9G4-2B4G3
Isotype
IgG1
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Discover our top product CHIT1 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for Chitotriosidase 1
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Target
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
Alternative Name
CHIT1 (CHIT1 Products )
Synonyms
CHI3 antibody, CHIT antibody, CHITD antibody, CHIT1 antibody, chio antibody, 2300002L19Rik antibody, chitinase 1 antibody, chitinase 1 (chitotriosidase) antibody, CHIT1 antibody, chit1 antibody, Chit1 antibody
Background
CHIT1 is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Synonyms: Monoclonal CHIT1 antibody, Anti-CHIT1 antibody, Chitinase 1 antibody, Chitotriosidase antibody, CHIT antibody.
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