E2F2 antibody
Quick Overview for E2F2 antibody (ABIN932201)
Target
See all E2F2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Human
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Cross-Reactivity (Details)
- Other species not studied.
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Purification
- Protein G affinity chromatography
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Immunogen
- E2 F2 antibody was raised in mouse using recombinant Human E2 Transcription Factor 2 (E2 2)
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Isotype
- IgG2a
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Application Notes
- Optimal conditions should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- E2 F2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- E2F2 (E2F Transcription Factor 2 (E2F2))
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Alternative Name
- E2F2
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Background
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. Synonyms: Monoclonal E2F2 antibody, Anti-E2F2 antibody, E2F transcription factor 2 antibody, E2F-2 antibody,.
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Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
Target
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