Fibulin 5 antibody

Catalog No. ABIN932743

This Mouse Monoclonal antibody specifically detects Fibulin 5 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Fibulin 5 antibody (ABIN932743)

Target: Fibulin 5 (FBLN5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3F8D5-7F8D5

Product Details anti-Fibulin 5 Antibody

Immunogen: Fibulin 5 antibody was raised in Mouse using a purified recombinant fragment of Fibulin 5 expressed in E. coli as the immunogen.

Isotype: IgM

Application Details

Application Notes: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: Fibulin 5

Background: Fibulin 5 is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components. Synonyms: Monoclonal Fibulin 5 antibody, Anti-Fibulin 5 antibody, FBLN5 antibody, FBLN-5 antibody, FBLN 5 antibody.

Pathways: SARS-CoV-2 Protein Interactome