BCL3 antibody

Catalog No. ABIN933151

This Mouse Monoclonal antibody specifically detects BCL3 in WB, ICC and DB. It exhibits reactivity toward Human.

Quick Overview for BCL3 antibody (ABIN933151)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 2069E2a

Product Details anti-BCL3 Antibody

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: BCL3 antibody was raised in mouse using recombinant Human B-Cell Cll/Lymphoma 3 (Bcl3)

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: BCL3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Alternative Name: BCL3

Background: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. Synonyms: Monoclonal BCL3 antibody, Anti-BCL3 antibody, B-cell lymphoma 3 encoded protein antibody, BCL4 antibody, D19S37 antibody.

Pathways: NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus