TNFRSF1B antibody

Catalog No. ABIN933866

The Mouse Monoclonal anti-TNFRSF1B antibody is suitable to detect TNFRSF1B in samples from Human. It has been validated for ELISA.

Quick Overview for TNFRSF1B antibody (ABIN933866)

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF1B antibody is un-conjugated

Application: ELISA

Clone: KT30

Product Details anti-TNFRSF1B Antibody

Purification: Protein A affinity chromatography

Immunogen: TNFRII antibody was raised in Mouse using recombinant soluble human TNFRII-Fc fusion protein as the immunogen.

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Target Details for TNFRSF1B

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Alternative Name: TNFRII

Background: TNF RII is a high affinity receptor for TNF-alpha and -beta, potent mediators of multiple aspects of inflammatory immune responses. RII is a prototypic member of the TNF receptor superfamily and has been designated TNFRSF1B. Whereas all cell types are thought to express TNF RI, TNF RII expression is limited primarily to hematopoietic cells and cells of the immune system. Most of the biological functions of TNF are mediated via TNF RI. Synonyms: Monoclonal TNFRII antibody, Anti-TNFRII antibody, TNF RII antibody, TNF-RII antibody, p75 antibody, p80 antibody, Tumor Necrosis Factor Receptor II antibody, Tumor Necrosis Factor Receptor 2 antibody.

Pathways: NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway