GM-CSF antibody (HRP)

Catalog No. ABIN933919

This Rat Monoclonal antibody specifically detects GM-CSF in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for GM-CSF antibody (HRP) (ABIN933919)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This GM-CSF antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Clone: KT35

Product Details anti-GM-CSF Antibody (HRP)

Purification: Protein A affinity chromatography

Immunogen: GMCSF antibody was raised in Rat using recombinant human GM-CSF as the immunogen.

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.01 % thimerosal as a preservative

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Target Details for GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Alternative Name: GMCSF

Background: GMCSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and Mouse molecules are species-specific and exhibit no cross-species reactivity. Synonyms: Monoclonal GMCSF antibody, Anti-GMCSF antibody, GM-CSF antibody, GM CSF antibody, Granulocyte/Macrophage Colony-Stimulating Factor antibody, CSF-2 antibody, MGI-1GM antibody, pluripoietin-alpha antibody.

Pathways: JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin