CD25 antibody

Catalog No. ABIN933951

The Mouse Monoclonal anti-CD25 antibody (Clone M912289) (ABIN933951) specifically detects CD25 in WB, ELISA and Inhibition. The antibody is reactive with Human samples.

Quick Overview for CD25 antibody (ABIN933951)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD25 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Clone: M912289

Product Details anti-CD25 Antibody

Immunogen: IL2 Ra antibody was raised in mouse using recombinant human soluble IL-2 Receptor alpha as the immunogen.

Isotype: IgG2a kappa

Application Details

Application Notes: ELISA: 4-8 µg/mL, Inhibition: 1-1.5 µg/mL, ib: 0.2-0.4 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: IL2Ra

Background: IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines. IL3 is species-specific, variably glycosylated cytokine. Synonyms: Monoclonal IL2Ra antibody, Anti-IL2Ra antibody, IL-3 antibody, Interleukin 3 antibody,MCGF antibody, Mast cell growth factor antibody, Multi-CSF antibody, HCGF antibody, P-cell stimulation factor antibody.

Molecular Weight: 15.1 kDa (predicted detection band MW)

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation