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Integrin Alpha2b antibody (CD41) Primary Antibody

CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 unconjugated
Catalog No. ABIN94106
$364.32
Plus shipping costs $45.00
0.1 mg
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  • Target
    Reactivity
    Human
    Host
    Mouse
    Clonality
    Monoclonal
    Conjugate
    This Integrin Alpha2b antibody is un-conjugated
    Application
    Flow Cytometry (FACS)
    Specificity
    The antibody MEM-06 reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
    Workshop: HLDA 10
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Leukocytes of patient suffering from LGL-type leukaemia.
    Clone
    MEM-06
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
  • Target
    Alternative Name
    CD41 (CD41 Antibody Abstract)
    Synonyms
    AI172977, CD41, CD41B, GpIIb, alphaIIb, BDPLT16, BDPLT2, GP2B, GPIIb, GT, GTA, HPA3, integrin alpha 2b, integrin subunit alpha 2b, Itga2b, ITGA2B
    Background
    CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
    Pathways
    Integrin Complex
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