Integrin Alpha2b antibody
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- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin Alpha2b antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- The antibody MEM-06 reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Immunogen
- Leukocytes of patient suffering from LGL-type leukaemia.
- Clone
- MEM-06
- Isotype
- IgG1
- Top Product
- Discover our top product CD41 Primary Antibody
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reactivity: Human FACS, ELISA, IHC Host: Mouse Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 45-149) antibodyCD41 Reactivity: Human FACS, WB, ELISA, IHC Host: Mouse Monoclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- CD41 (CD41 Products)
- Background
- Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GTA
- Gene ID
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
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