Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Cytokeratin 18 antibody (Keratin 18) (Biotin) Primary Antibody

KRT18 Reactivity: Mammalian ELISA, FACS, ICC, IHC (p), IP, WB Host: Mouse Monoclonal C-04 Biotin
Pubmed (4)
Catalog No. ABIN94280
$417.45
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 5 to 7 Business Days
  • Target See all Cytokeratin 18 (KRT18) Antibodies
    Cytokeratin 18 (KRT18)
    Reactivity
    • 325
    • 157
    • 125
    • 63
    • 43
    • 43
    • 37
    • 33
    • 30
    • 26
    • 24
    • 22
    • 22
    • 22
    • 9
    • 8
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Mammalian
    Host
    • 185
    • 158
    • 7
    • 6
    • 2
    • 1
    Mouse
    Clonality
    • 201
    • 158
    Monoclonal
    Conjugate
    • 166
    • 28
    • 23
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    This Cytokeratin 18 antibody is conjugated to Biotin
    Application
    • 224
    • 135
    • 130
    • 109
    • 82
    • 68
    • 58
    • 54
    • 41
    • 40
    • 33
    • 27
    • 12
    • 10
    • 8
    • 7
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
    Specificity
    The antibody C-04 reacts with Cytokeratin 18 (45 kDa), a member of intermediate filaments subfamily represented in epithelial tissues.
    Cross-Reactivity (Details)
    Mammalian
    Immunogen
    Cytoskeleton preparation of epidermal carcinoma cell line A431.
    Clone
    C-04
    Isotype
    IgG1
  • Application Notes
    The reagent is designed for Flow cytometry. Suggested working dilution is 1:500. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
    Comment

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Avoid prolonged exposure to light.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
  • Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991 (PubMed).

    Vojt?sek, Stasková, Nenutil, Lauerová, Kovarík, Rejthar, Bártková, Bártek: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." in: Folia biologica, Vol. 35, Issue 6, pp. 373-82, 1990 (PubMed).

    Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." in: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, 1989 (PubMed).

    Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989 (PubMed).

  • Target
    Cytokeratin 18 (KRT18)
    Alternative Name
    Cytokeratin 18 (KRT18 Products)
    Synonyms
    CK18, K18, Krt1-18, CYK18, DreK18, cb83, dapk1, sb:cb83, wu:fa13f02, wu:fb36b04, krt18, MGC64569, MGC75922, KRT18, keratin 18, keratin 18, type I L homeolog, keratin 18, type I, keratin, type I cytoskeletal 18, K18, simple type I keratin, Keratin, type I cytoskeletal 18, Krt18, KRT18, krt18, krt18.L, LOC700569, LOC100136778, k1c18, LOC100008885
    Background
    Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.Cytokeratins 18 belongs to type I family (acidic cytokeratins).
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
You are here:
help Support