Cyclin D1 antibody (AA 1-295)

Catalog No. ABIN947608

This Mouse Polyclonal antibody specifically detects Cyclin D1 in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Cyclin D1 antibody (AA 1-295) (ABIN947608)

Target: Cyclin D1 (CCND1)

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This Cyclin D1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin D1 Antibody

Binding Specificity: AA 1-295

Purpose: Mouse polyclonal antibody raised against a full-length human CCND1 protein.

Sequence: MEHQLLCCEV ETIRRAYPDA NLLNDRVLRA MLKAEETCAP SVSYFKCVQK EVLPSMRKIV ATWMLEVCEE QKCEEEVFPL AMNYLDRFLS LEPVKKSRLQ LLGATCMFVA SKMKETIPLT AGKLCIYTDN SIRPEELLQM ELLLVNKLKW NLAAMTPHDF IEHFLSKMPE AEENKQIIRK HAQTFVALCA TDVKFISNPP SMVAAGSVVA AVQGLNLRSP NNFLSYYRLT RFLSRVIKCD PDCLRACQEQ IEALLESSLR QAQQNMDPKA AEEEEEEEEE VDLACTPTDV RDVDI

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: CCND1 (AAH01501, 1 a.a. ~ 295 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Cyclin D1 antibody (ABIN947608)

Dannenmann, Hermanns, Bransi, Matter, von Boehmer, Stevanovic, Schraml, Moch, Knuth, van den Broek: "Spontaneous peripheral T-cell responses toward the tumor-associated antigen cyclin D1 in patients with clear cell renal cell carcinoma." in: Cancer immunology research, Vol. 1, Issue 5, pp. 288-95, (2014) (PubMed).

Target Details for Cyclin D1

Target: Cyclin D1 (CCND1)

Alternative Name: CCND1

Background: Full Gene Name: cyclin D1
Synonyms: BCL1,D11S287E,PRAD1,U21B31

Gene ID: 595

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling