SMPD3 antibody (AA 1-655)

Catalog No. ABIN949454

The Rabbit Polyclonal anti-SMPD3 antibody has been validated for WB and IP. It is suitable to detect SMPD3 in samples from Human. There are 2+ publications available.

Quick Overview for SMPD3 antibody (AA 1-655) (ABIN949454)

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SMPD3 Antibody

Binding Specificity: AA 1-655

Purpose: Rabbit polyclonal antibody raised against a full-length human SMPD3 protein.

Sequence: MVLYTTPFPN SCLSALHCVS WALIFPCYWL VDRLAASFIP TTYEKRQRAD DPCCLQLLCT ALFTPIYLAL LVASLPFAFL GFLFWSPLQS ARRPYIYSRL EDKGLAGGAA LLSEWKGTGP GKSFCFATAN VCLLPDSLAR VNNLFNTQAR AKEIGQRIRN GAARPQIKIY IDSPTNTSIS AASFSSLVSP QGGDGVARAV PGSIKRTASV EYKGDGGRHP GDEAANGPAS GDPVDSSSPE DACIVRIGGE EGGRPPEADD PVPGGQARNG AGGGPRGQTP NHNQQDGDSG SLGSPSASRE SLVKGRAGPD TSASGEPGAN SKLLYKASVV KKAAARRRRH PDEAFDHEVS AFFPANLDFL CLQEVFDKRA ATKLKEQLHG YFEYILYDVG VYGCQGCCSF KCLNSGLLFA SRYPIMDVAY HCYPNKCNDD ALASKGALFL KVQVGSTPQD QRIVGYIACT HLHAPQEDSA IRCGQLDLLQ DWLADFRKST SSSSAANPEE LVAFDVVCGD FNFDNCSSDD KLEQQHSLFT HYRDPCRLGP GEEKPWAIGT LLDTNGLYDE DVCTPDNLQK VLESEEGRRE YLAFPTSKSS GQKGRKELLK GNGRRIDYML HAEEGLCPDW KAEVEEFSFI TQLSGLTDHL PVAMRLMVSS GEEEA

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: SMPD3 (NP_061137.1, 1 a.a. ~ 655 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: No additive

Preservative: Without preservative

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SMPD3 antibody (ABIN949454)

Broner, Tropé, Reich, Davidson: "TSAP6 is a novel candidate marker of poor survival in metastatic high-grade serous carcinoma." in: Human pathology, Vol. 60, pp. 180-187, (2016) (PubMed).

Lee, Tan, Venkatratnam, Tan, Cui, Loh, Griffith, Tannenbaum, Chan: "Dysregulated sphingolipid metabolism in endometriosis." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 10, pp. E1913-21, (2014) (PubMed).

Target Details for SMPD3

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Alternative Name: SMPD3

Background: Full Gene Name: sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
Synonyms: FLJ22593,MGC138443,NSMASE2

Gene ID: 55512

NCBI Accession: NM_018667

Pathways: Hormone Transport